Product Description

Anti – p16/INK4A.

p16/INK4A is a tumour-suppressor protein and that genetic and epigenetic abnormalities in genes controlling the G1 checkpoint can lead to both escape from senescence and cancer formation. The interaction of p16/INK4 family members can be a binary complex with CDK4/6 or ternary complex with cyclin D-bound CDK4/6 and ultimately results in the inhibition of cell cycle progression. As such, expression of p16 INK4A is commonly associated with cellular senescence, and disruption of the p16 INK4A gene is frequently observed in human tumor. The p16/INK4A locus is deleted in a wide spectrum of tumors including melanoma, pancreatic adenocarcinoma, glioblastoma, certain leukemias, non-small cell lung cancer, cervical cancer, and bladder carcinoma.

Product Details

Manufacturer Biogenex
Unit 10ml
Code AM540-10M
For sale in GBR NIR IRL
Launch Diagnostics is a licensed reseller and distributor of p16 (INK4a) Mouse monoclonal

Launch Diagnostics is one of the major independent distributors in the U.K, providing high quality diagnostic reagents and instrumentation from world leading manufacturer’s to the Health Services of the United Kingdom, France, Belgium, Netherlands, Luxemburg and North Africa and to the Republic of Ireland through ACCUSAY Diagnostics.

Offering a large portfolio of diagnostic kits, laboratory instrumentation and services, our product range has expanded over the years to include a comprehensive range of EIA, single test devices, serology products, molecular assays and instrumentation.

Histology